Hypertonic saline dextran (HSD)

[DiverMedic]

The protocol is 2x 250 ml dose of HSD, followed by isotonic fluids. The Holcroft study I referenced speaks of decreased effectiveness will any more doses than that. Other sources concur.

Even tho the protocol is 2x 250cc HSD, typically in the field/UAS we have been sticking to 1x250cc followed by N/S.  The reason for that is the previous ROTO found that with a BP sub 100, after administration of 250cc HSD the BP would jump to roughly 180.  Not good for any clots that may have already formed.

Bare in mind, this isn't SOP, just practise in the field.

DM